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| Registros recuperados: 12 | |
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| Giani,Tania Santos; Paoli,Severo de; Presta,Giuseppe Antonio; Maiworm,Adalgisa Ieda; Santos-Filho,Sebastião David; Brandão-Neto,José; Medeiros,Aldo da Cunha; Fonseca,Adenilson de Souza da; Bernardo-Filho,Mario. |
| Buzhong Yi Qi Wan (Buzhong) is a medicinal herb widely used in Traditional Chinese Medicine to treat the digestive and circulatory systems. Red blood cell and plasma proteins labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this work was to investigate the effects of an aqueous Buzhong extract on the labeling of blood constituents with 99mTc. Heparinized blood (Wistar rats) was incubated in vitro with different Buzhong extract concentrations and 99mTc-labeling was performed. Plasma (P) and blood cells (BC) were separated and soluble (SF-P, SF-BC) and insoluble (IF-P, IF-BC) fractions were isolated. The radioactivity on blood constituents was determined and the percentage of incorporated radioactivity (%ATI) was calculated.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Technetium-99m; Red blood cell; Oxidant agent; Radiobiocomplex; Plasma proteins; Buzhong Yi Qi Wan. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600013 |
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| Batista,Jael Soares; Olinda,Roberio Gomes; Medeiros,Vitor Brasil; Rodrigues,Carla Monadeli Filgueira; Oliveira,Andréia Freitas; Paiva,Erika Souza; Freitas,Carlos Iberê Alves; Medeiros,Aldo da Cunha. |
| O objetivo deste estudo foi avaliar a atividade antibacteriana in vitro e cicatrizante do óleo de buriti (M. flexuosa) em feridas realizadas em ratos (Rattus norvegicus albinus). Para a avaliação antibacteriana in vitro, foram utilizados cinco patógenos bacterianos incluindo espécies gram-positivas e espécies gram-negativas mediante o uso do método de difusão em ágar. Para a avaliação da atividade cicatrizante, foram utilizados 40 ratos da linhagem Wistar, divididos em dois grupos: o grupo I, composto por 20 ratos com feridas cutâneas, tratados com aplicação tópica do creme base com 10% de óleo de buriti, e o grupo II, controle, com o mesmo número de animais que receberam a aplicação tópica do creme base. A aplicação do produto foi realizada em feridas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ação antibacteriana; Processo cicatricial; Ferida; Óleo de buriti; M. flexuosa. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782012000100022 |
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| Meyer,Patricia Froes; Santos-Filho,Sebastião David; Ronzio,Oscar Ariel; Bonelli,Ludmila; Fonseca,Adenilson de Souza da; Costa,Iris do Ceu Clara; Brandão Neto,José; Medeiros,Aldo da Cunha; Bernardo-Filho,Mario. |
| Sources of magnetic field, radiofrequency and audible sonic waves and pulsed light have been used in physiotherapy to treat different disorders. In nuclear medicine, blood constituents(Bl-Co) are labeled with technetium-99m (99mTc) are used. This study evaluated the consequences of magnetic field, radiofrequency and audible sonic waves and intense pulsed light sources on the labeling of Bl-Co with 99mTc. Blood from Wistar rats was exposed to the cited sources. The labeling of Bl-Co with 99mTc was performed. Blood not exposed to the physical agents was used(controls). Data showed that the exposure to the different studied sources did not alter significantly (p>0.05) the labeling of Bl-Co. Although the results were obtained with animals, the data suggest... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Blood constituents; Magnetic field; Sonic and radiofrequency waves; Technetium-99m. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600014 |
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| Silva,Roseane Pereira da; Holanda,Cecília Maria de Carvalho Xavier; Barbosa,Vanessa Santos de Arruda; Oliveira,Daniel Pereira de; Lima,Natália Alves; Câmara,Antônia Cláudia Jácome da; Medeiros,Aldo da Cunha; Constantino,Maria Helena Spyrides. |
| Artemisia vulgaris (AV) is an antihelmintic and antimalarial drug; Aloe vera(babosa) acts as antidiabetic, laxative and anti-inflammatory;Benznidazole (BZ) is a trypanocidal of Trypanosoma cruzi (TC). Technetium-99m (99mTc) has been used in nuclear medicine to obtain diagnostic images. This study evaluated the plant effects in TC parasitemia and on the biodistribution of 99mTc in mice. Twenty mice were infected by TC. At the peak of parasitemia, 5 mice received babosa; 5 received AV and 5 received BZ. The parasitemia was determined at 0, 2, 4 and 6 h of drugs administration. Five infected mice without drugs, 5 mice without TC and the group treated with AV, received 99mTc. The radioactivity was calculated. Infected mice that received babosa reduced... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aloe vera; Artemisia vulgaris; Technetium-99m; Trypanosoma cruzi; Parasitemia; Biodistribution. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700034 |
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| Holanda,Cecília Maria de Carvalho Xavier; Oliveira,Elias Herculano de; Rocha,Louisianny Guerra da; Barbosa,Vanessa Santos de Arruda; Spyrides,Maria Helena Constantino; Aragão,Cícero Flávio Soares; Medeiros,Aldo da Cunha. |
| The evidence that natural or synthetic drugs can affect the biodistribution of radiopharmaceuticals (radiobiocomplexes) in setting of nuclear medicine clinic is already known. We studied the effect of Paclitaxel, an anti-neoplastic agent for the treatment of solid tumors, on the biodistribution of Na99mTcO4 in female rats. Paclitaxel (1mg/mL/week) was administered into animals in single dose during 3 weeks, with interval of 1 week among them. The control group received NaCl 0.9% solutions by the same via. One hour after the last dose, it was injected Na99mTcO4 in the animals. The percentage of activity per gram (%ATI/g) and biochemical and hematological determinations were performed. A significant increase were found in alanine aminotransferase, aspartate... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Paclitaxel; Drug interaction; Radiopharmaceuticals; Na99mTcO4; Antitumoral drug; Cancer. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700031 |
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| Paoli,Severo de; Giani,Tania Santos; Presta,Giuseppe Antonio; Pereira,Marcia Oliveira; Fonseca,Adenilson de Souza da; Brandão-Neto,José; Medeiros,Aldo da Cunha; Santos-Filho,Sebastião David; Bernardo-Filho,Mário. |
| Clove (Caryophyllus aromaticus L.) has been used for clinical procedures. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this work was to evaluate the effects of clove extract on the labeling blood constituents with 99mTc and on the morphology of red blood cells. Blood samples were incubated with clove, stannous chloride and 99mTc. Plasma, blood cells, insoluble fractions of plasma and blood cells were separated. The radioactivity was counted and percentage of radioactivity (%ATI) to each blood fraction was calculated. The shape and morphometric parameter (perimeter/area ratio) were evaluated. Clove extract altered significantly (p<0.05) the %ATI of blood constituents and the shape of red blood cells... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Technetium-99m; Blood constituents; Red blood cells; Morphology; Caryophyllus aromaticus L. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600022 |
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| Duarte,Valéria Morgiana Gualberto; Rodrigues,Alanna de Sousa; Rezende,Luciana Augusto de; Ramos,Ana Maria de Oliveira; Souza,Rodrigo Medeiros de; Freire Neto,Francisco Paulo; Medeiros,Aldo da Cunha; Brandão Neto,José; Almeida,Maria das Graças; Rezende,Adriana Augusto de. |
| The relationship between lipid peroxidation, antioxidant defense and diabetic osteopenia remains unclear. This study evaluated the relationship among lipid peroxidation index, antioxidant defense parameters and bone metabolism in a premenopausal diabetic model using measures including thiobarbituric acid-reactive substances concentration (TBARS) and reduced glutathione (GSH) content in brain homogenates, histomorphometric analysis, biomechanical testing and bone mineral density (BMD). Female Wistar rats with regular estrous cycle were divided into two groups: Group 1: control rats (n = 15) and Group 2: diabetic rats (n = 15). Diabetes was induced by alloxan and confirmed by glycemia >250 mg/dL. The lipid peroxidation index, measured by TBARS... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oxidative stress; Lipid peroxidation; Diabetes mellitus; Diabetic osteopenia/experimental study. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300018 |
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| Registros recuperados: 12 | |
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